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pentobarbital will minimize the level or effect of naloxegol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Usage of naloxegol with robust CYP3A4 inducers is not advisedpentobarbital will minimize the extent or effect of eltrombopag by influencing hepatic enzyme CYP2C9/ten metabolism. Use Warning/Keep an eye on.pentoba